Nucleated RBC %
Learn about Nucleated RBC percentage for bone marrow stress assessment. Monitor blood cell production under stress conditions.
What is Nucleated RBC %?
Nucleated RBC % measures the percentage of nucleated red blood cells among total blood cells counted in the white cell channel. These are immature red blood cells that retain their nucleus, which should normally be extruded before cells enter circulation. Their presence typically indicates stress on the bone marrow or blood-forming system.
Why is it Tested?
Doctors order nucleated RBC % to assess bone marrow function, evaluate severe anemia, investigate blood disorders, and monitor treatment response in hematologic conditions. The presence of these cells helps identify conditions causing premature release of immature red cells into circulation.
Normal Ranges
Reference ranges vary by lab and methodology. Generally:
- Adults: 0% (typically undetectable)
Healthy adults should have no detectable nucleated red blood cells in peripheral blood circulation, as these cells normally mature completely in bone marrow before release.
Reference ranges vary by authority. Track yours across multiple standards with automatic unit conversions in LabsVault.
What do Abnormal Results Mean?
Abnormal results are not a diagnosis. Always discuss your results with a qualified healthcare provider before making any medical decisions.
Normal Nucleated RBC %
Zero or undetectable percentages indicate:
- Normal bone marrow function
- Proper red cell maturation
- No significant stress on blood-forming organs
High Nucleated RBC %
Any detectable nucleated RBCs warrant medical attention and may indicate:
- Severe anemia with bone marrow stress
- Hemolytic anemia
- Myelofibrosis or bone marrow infiltration
- Erythroleukemia
- Severe hypoxia
- Recovery from severe blood loss
- Spleen removal (splenectomy)
How to Track Over Time
Nucleated RBC percentages require prompt medical evaluation when detected. Serial monitoring helps assess bone marrow recovery and treatment response in severe anemias or blood disorders. Declining percentages typically indicate successful treatment and restoration of normal red cell maturation processes.
Track your Nucleated RBC % results over time
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