Globulin

Understand Globulin levels for immune function and protein balance evaluation. Learn about blood protein monitoring for wellness.

GLOB · g/dL · aka SERUM GLOBULIN, TOTAL GLOBULIN

What is Globulin?

Globulin represents a group of proteins in your blood that includes antibodies (immunoglobulins), transport proteins, and enzymes. These proteins are produced primarily by the liver and immune system cells, serving crucial roles in immunity and substance transport.

Why is it Tested?

Doctors measure globulin to assess immune function, evaluate liver protein synthesis, investigate inflammatory conditions, and diagnose certain diseases. It’s calculated as part of liver function tests and helps interpret total protein levels.

Normal Ranges

Reference ranges for globulin:

  • Normal: 2.0–3.5 g/dL

Globulin is typically calculated by subtracting albumin from total protein, so it reflects the remaining protein fraction.

Reference ranges vary by authority. Track yours across multiple standards with automatic unit conversions in LabsVault.

What do Abnormal Results Mean?

Abnormal results are not a diagnosis. Always discuss your results with a qualified healthcare provider before making any medical decisions.

Low Globulin

Reduced levels may indicate:

  • Immunodeficiency disorders
  • Liver disease
  • Malnutrition
  • Kidney disease with protein loss
  • Certain genetic conditions

High Globulin

Elevated levels suggest:

  • Chronic inflammation or infection
  • Autoimmune disorders
  • Multiple myeloma or other blood cancers
  • Liver disease (cirrhosis)
  • Dehydration

How to Track Over Time

Globulin levels help monitor immune system function and chronic inflammatory conditions. Persistent elevations may indicate ongoing inflammation or immune system disorders, while declining levels during treatment suggest successful intervention. The albumin-to-globulin ratio provides additional diagnostic information.

Track your Globulin results over time

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