Fibrinogen

Track Fibrinogen levels for blood clotting function and cardiovascular health. Learn about coagulation factor monitoring.

FIB · mg/dL · aka fibrinogen activity, factor I

What is Fibrinogen?

Fibrinogen is a protein produced by the liver that plays essential roles in blood clotting and inflammation. During clotting, fibrinogen converts to fibrin to form blood clots. It also acts as an acute-phase reactant, rising during inflammation, infection, or tissue damage.

Why is it Tested?

Doctors order fibrinogen to evaluate bleeding disorders, assess clotting function before surgery, or investigate unexplained bleeding or clotting episodes. It’s also used as an inflammatory marker and to assess cardiovascular disease risk in some patients.

Normal Ranges

Reference ranges vary by lab:

  • Adults: 200–400 mg/dL

Fibrinogen levels can increase with age, pregnancy, inflammation, and certain medications including oral contraceptives and hormone replacement therapy.

Reference ranges vary by authority. Track yours across multiple standards with automatic unit conversions in LabsVault.

What do Abnormal Results Mean?

Abnormal results are not a diagnosis. Always discuss your results with a qualified healthcare provider before making any medical decisions.

Low Fibrinogen

Decreased levels may indicate:

  • Congenital fibrinogen deficiency
  • Severe liver disease
  • Disseminated intravascular coagulation (DIC)
  • Malnutrition
  • Certain blood-thinning medications

High Fibrinogen

Elevated levels may suggest:

  • Acute inflammation or infection
  • Cardiovascular disease risk
  • Certain cancers
  • Pregnancy
  • Smoking or metabolic syndrome

How to Track Over Time

Fibrinogen levels fluctuate with inflammatory conditions and gradually increase with cardiovascular risk factors. Tracking trends helps monitor inflammatory disease activity and assess cardiovascular risk reduction strategies including lifestyle changes and anti-inflammatory treatments.

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